Tsukumo Ryusuke is a quirky, yet brilliant neuroscientist working for the National Research Institute of Police Science. Wielding a unique perspective and psychology, Tsukumo tackles the nation’s most baffling crimes and scandals, going head-to-head with the most brilliant and twisted criminal minds. But his eccentricities and poor social timing can also aggravate people and circumstances, further complicating matters.

Mr. Brain starring Kimura Takuya as Tsukumo Ryusuke and Ayase Haruka as Yuri Kazune and there are plenty more great japanese actors. The drama is about Tsukumo (Kimura) he was a male hostess till one day part of a building collapsed on him and punctured parts of his brain and he survived but his personality changed and he became some kind of genius.

                Geon Ok (Kim Nam-Gil) is a sexy man & highly ambitious. Geon Ok attempts to get a Chaebol group by using his fatal charms and cunning mind. Jane (Han Ga-In) is a strong women who stands by her man, Geon Ok. She will attempt to protect their love.

               Tera (Oh Yeon-Su) was born as the first daughter in a Chaebol family. She has never said no to her parents and went through an arranged marriage. She lives her life like the typical upperclass housewife. She then meets Geon Ok and throws herself into a heated affair.